Given the already formed research question of your study which analyzes the impact of a given treatment or therapy (prevention and education support services) on patients with a given condition (recently diagnosed HIV), a randomized, controlled study design would best fit your research. In a randomized, controlled study, which is by the way, the standard design for this type of research, you would randomly place the participants in two groups. Both groups would of course receive the standard HIV medical treatments. However, one group would receive prevention and education support services and the other would receive just the standard medical treatment. The impact of the education on the quality of life of the group receiving the services would be compared to the quality of life of the group that did not to determine the education services impact.
A simple random sampling method works best in this situation where there is one group (the HIV positive women) and one needs to create a subgroup. Drawing names or using a computer program to randomly select the subgroup, dividing the group into two, are two common methods of creating a sampling. Once divided, one group receives the treatment, prevention and education support services, while the other does not. Overtime, the impact of the prevention and education support service is qualitatively described and evaluated to determine its impact.
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